I Am a Man of Constant Sorrow

Funny country pills.
From the movie; "O' Brother Where Art Thou?" That's George Clooney appearing on lead vocals, with Tim Blake Nelson and John Turturro accompanying, but the voices belong to Dan Tyminski and Union Station. Notice the cameo by Stephen Root as the blind Radio Station manager, he was also the voice of Chode in "Tripping the Rift" and played Jimmy James in "News Radio" and Milton Waddums in "Office Space."